› 2hei

X-ray diffraction
1.55Å resolution

Crystal structure of human RAB5B in complex with GDP

Released:
DOI: 10.2210/pdb2hei/pdb
PDB entry 2hei coloured by chain, front view.
PDB entry 2hei coloured by chain, side view.
PDB entry 2hei coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Hong B, Shen L, Wang J, Tempel W, Landry R, Arrowsmith CH, Edwards AM, Sundstrom M, Weigelt J, Bochkarev A, Park H, Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed: 
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158182 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ras-related protein Rab-5B Chains: A, B
Molecule details ›
Chains: A, B
Length: 179 amino acids
Theoretical weight: 19.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61020 (Residues: 15-191; Coverage: 82%)
Gene name: RAB5B
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:
Ligand GDP 2 x GDP
Ligand D1D 2 x D1D
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: P212121
Unit cell:
a: 41.302Å b: 78.37Å c: 95.501Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.264 0.262 0.294
Expression system: Escherichia coli

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