› 2hi3

Solution NMR

Solution structure of the homeodomain-only protein HOP

Released:
DOI: 10.2210/pdb2hi3/pdb
PDB entry 2hi3 coloured by chain, ensemble of 20 models, front view.
PDB entry 2hi3 coloured by chain, ensemble of 20 models, side view.
PDB entry 2hi3 coloured by chain, ensemble of 20 models, top view.
Source organism: Mus musculus
Primary publication:
Analysis of the structure and function of the transcriptional coregulator HOP.
Kook H, Yung WW, Simpson RJ, Kee HJ, Shin S, Lowry JA, Loughlin FE, Yin Z, Epstein JA, Mackay JP
Biochemistry 45 10584-90 (2006)
PMID: 16939210

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185875 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Homeodomain-only protein Chain: A
Molecule details ›
Chain: A
Length: 73 amino acids
Theoretical weight: 8.32 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q8R1H0 (Residues: 1-73; Coverage: 100%)
Gene names: Hod, Hop, Hopx, Ob1
Sequence domains: Homeodomain
Structure domains: Homeodomain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli BL21

Quick links

Citations

5 review citations

Homeodomain proteins: an update.
Bürglin et al. (2016)
4 more

2 mentions without citation

Crystal structure of the three tandem FF domains of the transcription elongation regulator CA150.
Lu et al. (2009)
1 more