› 2hto

X-ray diffraction
1.54Å resolution

Ruthenium hexammine ion interactions with Z-DNA

Released:
DOI: 10.2210/pdb2hto/pdb
PDB entry 2hto coloured by chain, front view.
PDB entry 2hto coloured by chain, side view.
PDB entry 2hto coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Hexammineruthenium(III) ion interactions with Z-DNA.
Bharanidharan D, Thiyagarajan S, Gautham N
Acta Crystallogr Sect F Struct Biol Cryst Commun 63 1008-13 (2007)
PMID: 18084080

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-115367 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
DNA (5'-D(*DCP*DGP*DCP*DGP*DCP*DA)-3') Chain: A
Molecule details ›
Chain: A
Length: 6 nucleotides
Theoretical weight: 1.79 KDa
Source organism: Synthetic construct
Expression system: Not provided
DNA (5'-D(*DTP*DGP*DCP*DGP*DCP*DG)-3') Chain: B
Molecule details ›
Chain: B
Length: 6 nucleotides
Theoretical weight: 1.83 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand NRU 1 x NRU
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P212121
Unit cell:
a: 17.953Å b: 30.821Å c: 44.596Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.189 0.217
Expression system: Not provided

Quick links

Citations

3 citation in other articles

On the interaction between [Ru(NH3)6]3+ and the G-quadruplex forming thrombin binding aptamer sequence.
De Rache et al. (2013)
2 more

2 mentions without citation

Phosphates in the Z-DNA dodecamer are flexible, but their P-SAD signal is sufficient for structure solution.
Luo et al. (2014)
1 more