› 2i1n

X-ray diffraction
1.85Å resolution

Crystal structure of the 1st PDZ domain of Human DLG3

Released:
DOI: 10.2210/pdb2i1n/pdb
PDB entry 2i1n coloured by chain, front view.
PDB entry 2i1n coloured by chain, side view.
PDB entry 2i1n coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Elkins JM, Papagrigoriou E, Berridge G, Yang X, Phillips C, Gileadi C, Savitsky P, Doyle DA
Protein Sci 16 683-94 (2007)
PMID: 17384233

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-187755 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Disks large homolog 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 102 amino acids
Theoretical weight: 10.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q92796 (Residues: 126-222; Coverage: 12%)
Gene names: DLG3, KIAA1232
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

1 bound ligand:
Ligand NA 5 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: C2221
Unit cell:
a: 81.817Å b: 80.545Å c: 67.693Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.187 0.186 0.218
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Engineering of recombinant crystallization chaperones.
Koide S. (2009)
5 more

4 mentions without citation

The multiple-specificity landscape of modular peptide recognition domains.
Gfeller et al. (2011)
3 more