Function and Biology Details
Reaction catalysed:
Specific cleavage of Arg-|-Val bond in plasminogen to form plasmin.
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
uPA-uPAR complex (preferred)
PDBe Complex ID:
PDB-CPX-133293 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Urokinase-type plasminogen activator long chain A
Molecule details ›
Chains: A, B, C, D
Length: 145 amino acids
Theoretical weight: 16.4 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
Sequence domains: Kringle domain
Structure domains:
Length: 145 amino acids
Theoretical weight: 16.4 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
- Canonical:
P00749 (Residues: 21-163; Coverage: 35%)
Sequence domains: Kringle domain
Structure domains:
Urokinase plasminogen activator surface receptor
Molecule details ›
Chains: E, F, G, H
Length: 279 amino acids
Theoretical weight: 31.11 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
Sequence domains: u-PAR/Ly-6 domain
Structure domains: CD59
Length: 279 amino acids
Theoretical weight: 31.11 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
- Canonical: Q03405 (Residues: 23-299; Coverage: 89%)
Sequence domains: u-PAR/Ly-6 domain
Structure domains: CD59
