› 2i9h

Solution NMR

NMR solution structure of the reduced form of thioredoxin 1 from yeast (Trx1)

Released:
DOI: 10.2210/pdb2i9h/pdb
PDB entry 2i9h coloured by chain, ensemble of 20 models, front view.
PDB entry 2i9h coloured by chain, ensemble of 20 models, side view.
PDB entry 2i9h coloured by chain, ensemble of 20 models, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
NMR solution structure of the reduced form of thioredoxin 1 from Sacharomyces cerevisiae.
Pinheiro AS, Amorim GC, Netto LE, Almeida FC, Valente AP
Proteins 70 584-7 (2008)
PMID: 17932921

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149546 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin-1 Chain: A
Molecule details ›
Chain: A
Length: 103 amino acids
Theoretical weight: 11.24 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P22217 (Residues: 1-103; Coverage: 100%)
Gene names: TRX1, TRX2, YLR043C
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 91%
Refinement method: torsion angle simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

Conferring specificity in redox pathways by enzymatic thiol/disulfide exchange reactions.
Netto et al. (2016)
2 other articles

2 mentions without citation

Solution NMR structures of oxidized and reduced Ehrlichia chaffeensis thioredoxin: NMR-invisible structure owing to backbone dynamics.
Buchko et al. (2018)
1 more