Assemblies
Multimeric state:
hetero pentamer
Accessible surface area:
36028.47 Å2
Buried surface area:
13960.4 Å2
Dissociation area:
1,276.78
Å2
Dissociation energy (ΔGdiss):
0.51
kcal/mol
Dissociation entropy (TΔSdiss):
13.89
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-134726
Macromolecules
Chain: A
Length: 182 amino acids
Theoretical weight: 21.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Pfam:
InterPro:
SCOP:
Length: 182 amino acids
Theoretical weight: 21.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical: P01903 (Residues: 26-207; Coverage: 80%)
Pfam:
InterPro:
- MHC class II, alpha/beta chain, N-terminal
- MHC classes I/II-like antigen recognition protein
- MHC class II, alpha chain, N-terminal
- Immunoglobulin-like fold
- Immunoglobulin-like domain superfamily
- Immunoglobulin-like domain
- Immunoglobulin C1-set
- Immunoglobulin/major histocompatibility complex, conserved site
SCOP:
Chain: B
Length: 190 amino acids
Theoretical weight: 22.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Pfam:
InterPro:
SCOP:
Length: 190 amino acids
Theoretical weight: 22.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical: P01911 (Residues: 30-219; Coverage: 80%)
Pfam:
InterPro:
- MHC class II, alpha/beta chain, N-terminal
- MHC classes I/II-like antigen recognition protein
- Immunoglobulin-like fold
- Immunoglobulin-like domain superfamily
- Immunoglobulin-like domain
- Immunoglobulin C1-set
- Immunoglobulin/major histocompatibility complex, conserved site
- MHC class II, beta chain, N-terminal
SCOP:
Chain: P
Length: 15 amino acids
Theoretical weight: 1.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Length: 15 amino acids
Theoretical weight: 1.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical: P60174 (Residues: 23-37; Coverage: 6%)
Chain: C
Length: 202 amino acids
Theoretical weight: 22.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Pfam: Domain of unknown function (DUF1968)
InterPro:
Length: 202 amino acids
Theoretical weight: 22.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical: P01848 (Residues: 1-93; Coverage: 66%)
Pfam: Domain of unknown function (DUF1968)
InterPro:
- Immunoglobulin-like fold
- Immunoglobulin-like domain superfamily
- Immunoglobulin-like domain
- Immunoglobulin V-set domain
- Immunoglobulin subtype
- T-cell receptor alpha chain, constant domain
Chain: D
Length: 240 amino acids
Theoretical weight: 27.09 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Pfam: Immunoglobulin C1-set domain
InterPro:
Length: 240 amino acids
Theoretical weight: 27.09 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical: P01850 (Residues: 1-129; Coverage: 73%)
Pfam: Immunoglobulin C1-set domain
InterPro:
- Immunoglobulin-like fold
- Immunoglobulin-like domain superfamily
- Immunoglobulin-like domain
- Immunoglobulin C1-set
- Immunoglobulin V-set domain
- Immunoglobulin subtype