› 2ie1

X-ray diffraction
1.6Å resolution

Polyamines stabilize left-handed Z-DNA. We found new type of polyamine which stabilize left-handed Z-DNA by X-ray crystallography

Released:
DOI: 10.2210/pdb2ie1/pdb
PDB entry 2ie1 coloured by chain, front view.
PDB entry 2ie1 coloured by chain, side view.
PDB entry 2ie1 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Ohishi H, Odoko M, Tsukamoto K, Hiyama Y, Maezaki N, Grzeskowiak K, Ishida T, Tanaka T, Okabe N, Fukuyama K

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-115395 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*DCP*DGP*DCP*DGP*DCP*DG)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 6 nucleotides
Theoretical weight: 1.81 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand PAW 2 x PAW
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6A
Spacegroup: P212121
Unit cell:
a: 17.64Å b: 30.38Å c: 43.63Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.19 0.205
Expression system: Not provided

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