› 2if4

X-ray diffraction
2.85Å resolution

Crystal structure of a multi-domain immunophilin from Arabidopsis thaliana

Released:
DOI: 10.2210/pdb2if4/pdb
PDB entry 2if4 coloured by chain, front view.
PDB entry 2if4 coloured by chain, side view.
PDB entry 2if4 coloured by chain, top view.
Source organism: Arabidopsis thaliana
Primary publication:
Crystal structure of a multi-domain immunophilin from Arabidopsis thaliana: a paradigm for regulation of plant ABC transporters.
Granzin J, Eckhoff A, Weiergräber OH
J Mol Biol 364 799-809 (2006)
PMID: 17045295

Function and Biology Details

Reaction catalysed: 
Peptidylproline (omega=180) = peptidylproline (omega=0)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192266 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidyl-prolyl cis-trans isomerase FKBP42 Chain: A
Molecule details ›
Chain: A
Length: 338 amino acids
Theoretical weight: 38.36 KDa
Source organism: Arabidopsis thaliana
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9LDC0 (Residues: 1-338; Coverage: 93%)
Gene names: At3g21640, FKBP42, MIL23.21, TWD1, UCU2
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P21212
Unit cell:
a: 86.142Å b: 117.873Å c: 40.112Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.296 0.29 0.355
Expression system: Escherichia coli BL21

Quick links

Citations

5 review citations

Post-transcriptional regulation of auxin transport proteins: cellular trafficking, protein phosphorylation, protein maturation, ubiquitination, and membrane composition.
Titapiwatanakun et al. (2009)
4 more

5 mentions without citation

Structure-based classification of 45 FK506-binding proteins.
Somarelli et al. (2008)
4 more