› 2irm

X-ray diffraction
3Å resolution

Crystal structure of mitogen-activated protein kinase kinase kinase 7 interacting protein 1 from Anopheles gambiae

Released:
DOI: 10.2210/pdb2irm/pdb
PDB entry 2irm coloured by chain, front view.
PDB entry 2irm coloured by chain, side view.
PDB entry 2irm coloured by chain, top view.
Source organism: Anopheles gambiae
Primary publication:
Structural genomics of protein phosphatases.
Almo SC, Bonanno JB, Sauder JM, Emtage S, Dilorenzo TP, Malashkevich V, Wasserman SR, Swaminathan S, Eswaramoorthy S, Agarwal R, Kumaran D, Madegowda M, Ragumani S, Patskovsky Y, Alvarado J, Ramagopal UA, Faber-Barata J, Chance MR, Sali A, Fiser A, Zhang ZY, Lawrence DS, Burley SK
J Struct Funct Genomics 8 121-40 (2007)
PMID: 18058037

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181880 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
AGAP002953-PA Chain: A
Molecule details ›
Chain: A
Length: 358 amino acids
Theoretical weight: 39.7 KDa
Source organism: Anopheles gambiae
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7QD46 (Residues: 9-368; Coverage: 78%)
Gene name: AgaP_AGAP002953
Sequence domains: Protein phosphatase 2C
Structure domains: PPM-type phosphatase domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: C2
Unit cell:
a: 121.773Å b: 73.773Å c: 74.509Å
α: 90° β: 116.96° γ: 90°
R-values:
R R work R free
0.221 0.218 0.277
Expression system: Escherichia coli

Quick links

Citations

24 review citations

Aiding and abetting roles of NOX oxidases in cellular transformation.
Block et al. (2012)
23 more

1 mention without citation

Structural genomics of protein phosphatases.
Almo et al. (2007)