› 2jj6

X-ray diffraction
2Å resolution

Crystal structure of the putative carbohydrate recognition domain of the human galectin-related protein

Released:
DOI: 10.2210/pdb2jj6/pdb
PDB entry 2jj6 coloured by chain, front view.
PDB entry 2jj6 coloured by chain, side view.
PDB entry 2jj6 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the putative carbohydrate recognition domain of human galectin-related protein.
Wälti MA, Thore S, Aebi M, Künzler M
Proteins 72 804-8 (2008)
PMID: 18433051

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174903 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Galectin-related protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 134 amino acids
Theoretical weight: 15.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q3ZCW2 (Residues: 38-171; Coverage: 78%)
Gene names: GRP, HSPC159, LGALSL
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS
Spacegroup: P3221
Unit cell:
a: 78.391Å b: 78.391Å c: 89.883Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.217 0.217 0.259
Expression system: Escherichia coli

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Citations

1 review citation

Galectin-3 inhibitors: a patent review (2008-present).
Blanchard et al. (2014)
6 other articles