› 2jop

Solution NMR

Solution structure of the N-terminal extracellular domain of the lymphocyte receptor CD5 (CD5 domain 1)

Released:
DOI: 10.2210/pdb2jop/pdb
PDB entry 2jop coloured by chain, ensemble of 50 models, front view.
PDB entry 2jop coloured by chain, ensemble of 50 models, side view.
PDB entry 2jop coloured by chain, ensemble of 50 models, top view.
Source organism: Homo sapiens
Primary publication:
Three-dimensional solution structure and conformational plasticity of the N-terminal scavenger receptor cysteine-rich domain of human CD5.
Garza-Garcia A, Esposito D, Rieping W, Harris R, Briggs C, Brown MH, Driscoll PC
J Mol Biol 378 129-44 (2008)
PMID: 18339402

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138876 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
T-cell surface glycoprotein CD5 Chain: A
Molecule details ›
Chain: A
Length: 131 amino acids
Theoretical weight: 14.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P06127 (Residues: 25-134; Coverage: 23%)
Gene names: CD5, LEU1
Sequence domains: Scavenger receptor cysteine-rich domain
Structure domains: SRCR-like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 88%
Refinement method: DGSA-distance geometry simulated annealing
Expression system: Escherichia coli

Quick links

Citations

2 review citations

CD163 and inflammation: biological, diagnostic, and therapeutic aspects.
Etzerodt et al. (2013)
1 more

1 mention without citation

Isolation of anticancer bioactive secondary metabolites from the sponge-derived endophytic fungi Penicillium sp. and in-silico computational docking approach.
Kaliaperumal et al. (2023)