› 2jq6

Solution NMR

Structure of EH-domain of EHD1

Released:
DOI: 10.2210/pdb2jq6/pdb
PDB entry 2jq6 coloured by chain, ensemble of 10 models, front view.
PDB entry 2jq6 coloured by chain, ensemble of 10 models, side view.
PDB entry 2jq6 coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
EH domain of EHD1.
Kieken F, Jović M, Naslavsky N, Caplan S, Sorgen PL
J Biomol NMR 39 323-9 (2007)
PMID: 17899392

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190615 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
EH domain-containing protein 1 Chain: A
Molecule details ›
Chain: A
Length: 139 amino acids
Theoretical weight: 14.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9H4M9 (Residues: 401-534; Coverage: 25%)
Gene names: CDABP0131, EHD1, PAST, PAST1
Sequence domains: Cytoskeletal-regulatory complex EF hand
Structure domains: EF-hand

Ligands and Environments

1 bound ligand:
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 95%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21

Quick links

Citations

4 review citations

EHD proteins: key conductors of endocytic transport.
Naslavsky et al. (2011)
3 more

2 mentions without citation

The dipeptidyl peptidase IV inhibitors vildagliptin and K-579 inhibit a phospholipase C: a case of promiscuous scaffolds in proteins.
Chakraborty et al. (2013)
1 more