› 2jsn

Solution NMR

Solution structure of the atypical PDZ-like domain of synbindin

Released:
DOI: 10.2210/pdb2jsn/pdb
PDB entry 2jsn coloured by chain, ensemble of 20 models, front view.
PDB entry 2jsn coloured by chain, ensemble of 20 models, side view.
PDB entry 2jsn coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of synbindin atypical PDZ domain and interaction with syndecan-2.
Fan S, Feng Y, Wei Z, Xia B, Gong W
Protein Pept Lett 16 189-95 (2009)
PMID: 19200043

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195119 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Trafficking protein particle complex subunit 4 Chain: A
Molecule details ›
Chain: A
Length: 96 amino acids
Theoretical weight: 10.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y296 (Residues: 19-106; Coverage: 40%)
Gene names: CGI-104, HSPC172, PTD009, SBDN, TRAPPC4
Sequence domains: Sybindin-like family
Structure domains: Pdz3 Domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 79%
Refinement method: molecular dynamics, simulated annealing
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Transmembrane signaling proteoglycans.
Couchman JR. (2010)
3 more

1 mention without citation

The dipeptidyl peptidase IV inhibitors vildagliptin and K-579 inhibit a phospholipase C: a case of promiscuous scaffolds in proteins.
Chakraborty et al. (2013)