› 2jxx

Solution NMR

NMR solution structure of Ubiquitin-like domain of NFATC2IP. Northeast Structural Genomics Consortium target HR5627

Released:
DOI: 10.2210/pdb2jxx/pdb
PDB entry 2jxx coloured by chain, ensemble of 20 models, front view.
PDB entry 2jxx coloured by chain, ensemble of 20 models, side view.
PDB entry 2jxx coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Doherty RS, Dhe-Paganon S, Fares C, Lemak A, Butler C, Srisailam S, Karra M, Yee A, Edwards AM, Weigelt J, Arrowsmith CH, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185487 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NFATC2-interacting protein Chain: A
Molecule details ›
Chain: A
Length: 97 amino acids
Theoretical weight: 10.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8NCF5 (Residues: 342-419; Coverage: 19%)
Gene names: NFATC2IP, NIP45
Sequence domains: Ubiquitin-2 like Rad60 SUMO-like
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 89%
Refinement method: molecular dynamics
Expression system: Escherichia coli BL21(DE3)

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