› 2k21

Solution NMR

NMR structure of human KCNE1 in LMPG micelles at pH 6.0 and 40 degree C

Released:
DOI: 10.2210/pdb2k21/pdb
PDB entry 2k21 coloured by chain, ensemble of 10 models, front view.
PDB entry 2k21 coloured by chain, ensemble of 10 models, side view.
PDB entry 2k21 coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
Structure of KCNE1 and implications for how it modulates the KCNQ1 potassium channel.
Kang C, Tian C, Sönnichsen FD, Smith JA, Meiler J, George AL, Vanoye CG, Kim HJ, Sanders CR
Biochemistry 47 7999-8006 (2008)
PMID: 18611041

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147335 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Potassium voltage-gated channel subfamily E member 1 Chain: A
Molecule details ›
Chain: A
Length: 138 amino acids
Theoretical weight: 15.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P15382 (Residues: 1-129; Coverage: 100%)
Gene name: KCNE1
Sequence domains: Slow voltage-gated potassium channel

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DGSA-distance geometry simulated annealing
Expression system: Escherichia coli

Quick links

Citations

24 review citations

Ancillary subunits associated with voltage-dependent K+ channels.
Pongs et al. (2010)
23 more

21 mentions without citation

Use of electron paramagnetic resonance to solve biochemical problems.
Sahu et al. (2013)
20 more