› 2k35

Solution NMR

Hydramacin-1: Structure and antibacterial activity of a peptide from the basal metazoan Hydra

Released:
DOI: 10.2210/pdb2k35/pdb
PDB entry 2k35 coloured by chain, ensemble of 25 models, front view.
PDB entry 2k35 coloured by chain, ensemble of 25 models, side view.
PDB entry 2k35 coloured by chain, ensemble of 25 models, top view.
Source organism: Hydra
Primary publication:
Hydramacin-1, structure and antibacterial activity of a protein from the basal metazoan Hydra.
Jung S, Dingley AJ, Augustin R, Anton-Erxleben F, Stanisak M, Gelhaus C, Gutsmann T, Hammer MU, Podschun R, Bonvin AM, Leippe M, Bosch TC, Grötzinger J
J Biol Chem 284 1896-905 (2009)
PMID: 19019828

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-109903 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hydramacin-1 Chain: A
Molecule details ›
Chain: A
Length: 60 amino acids
Theoretical weight: 7.03 KDa
Source organism: Hydra
Expression system: Escherichia coli
UniProt:
  • Canonical: B3RFR8 (Residues: 25-84; Coverage: 100%)
Sequence domains: Macin
Structure domains: Defensin A-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

18 review citations

More than just orphans: are taxonomically-restricted genes important in evolution?
Khalturin et al. (2009)
17 more

4 mentions without citation

Macin family of antimicrobial proteins combines antimicrobial and nerve repair activities.
Jung et al. (2012)
3 more