› 2k7s

Solution NMR

Human ARNT C-Terminal PAS Domain, 3 Residue IB slip

Released:
DOI: 10.2210/pdb2k7s/pdb
PDB entry 2k7s coloured by chain, ensemble of 20 models, front view.
PDB entry 2k7s coloured by chain, ensemble of 20 models, side view.
PDB entry 2k7s coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
ARNT PAS-B has a fragile native state structure with an alternative beta-sheet register nearby in sequence space.
Evans MR, Card PB, Gardner KH
Proc Natl Acad Sci U S A 106 2617-22 (2009)
PMID: 19196990

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151024 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aryl hydrocarbon receptor nuclear translocator Chain: A
Molecule details ›
Chain: A
Length: 119 amino acids
Theoretical weight: 13.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P27540 (Residues: 356-470; Coverage: 15%)
Gene names: ARNT, BHLHE2
Sequence domains: PAS domain
Structure domains: PAS domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 89%
Refinement method: simulated annealing, torsion angle dynamics, molecular dynamics
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Structure and signaling mechanism of Per-ARNT-Sim domains.
Möglich et al. (2009)
1 more

5 mentions without citation

ARNT PAS-B has a fragile native state structure with an alternative beta-sheet register nearby in sequence space.
Evans et al. (2009)
4 more