› 2kfv

Solution NMR

Structure of the amino-terminal domain of human FK506-binding protein 3 / Northeast Structural Genomics Consortium Target HT99A

Released:
DOI: 10.2210/pdb2kfv/pdb
PDB entry 2kfv coloured by chain, ensemble of 20 models, front view.
PDB entry 2kfv coloured by chain, ensemble of 20 models, side view.
PDB entry 2kfv coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Sunnerhagen M, Davis T, Gutmanas A, Fares C, Ouyang H, Lemak A, Li Y, Weigelt J, Bountra C, Edwards A, Arrowsmith CH, Dhe-Paganon S, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed: 
Peptidylproline (omega=180) = peptidylproline (omega=0)
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169466 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidyl-prolyl cis-trans isomerase FKBP3 Chain: A
Molecule details ›
Chain: A
Length: 92 amino acids
Theoretical weight: 10.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q00688 (Residues: 1-73; Coverage: 33%)
Gene names: FKBP25, FKBP3
Sequence domains: Basic tilted helix bundle domain
Structure domains: Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 88%
Refinement method: molecular dynamics
Expression system: Escherichia coli

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