› 2khn

Solution NMR

NMR solution structure of the EH 1 domain from human intersectin-1 protein. Northeast Structural Genomics Consortium target HR3646E.

Released:
DOI: 10.2210/pdb2khn/pdb
PDB entry 2khn coloured by chain, ensemble of 20 models, front view.
PDB entry 2khn coloured by chain, ensemble of 20 models, side view.
PDB entry 2khn coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Mills JL, Ghosh A, Garcia E, Zhang Q, Shastry R, Foote EL, Janjua H, Acton TB, Xiao R, Everett JK, Montelione GT, Szyperski T, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172413 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Intersectin-1 Chain: A
Molecule details ›
Chain: A
Length: 121 amino acids
Theoretical weight: 13.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15811 (Residues: 1-111; Coverage: 6%)
Gene names: ITSN, ITSN1, SH3D1A
Sequence domains: Cytoskeletal-regulatory complex EF hand
Structure domains: EF-hand

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 78%
Refinement method: molecular dynamics
Expression system: Escherichia coli

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