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Solution NMR

Solution structure of human ubiquitin conjugating enzyme Ube2g2

Released:
DOI: 10.2210/pdb2kly/pdb
PDB entry 2kly coloured by chain, ensemble of 10 models, front view.
PDB entry 2kly coloured by chain, ensemble of 10 models, side view.
PDB entry 2kly coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure and dynamics of human ubiquitin conjugating enzyme Ube2g2.
Ju T, Bocik W, Majumdar A, Tolman JR
Proteins 78 1291-301 (2010)
PMID: 20014027

Function and Biology Details

Reaction catalysed: 
S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158051 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ubiquitin-conjugating enzyme E2 G2 Chain: A
Molecule details ›
Chain: A
Length: 167 amino acids
Theoretical weight: 18.78 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P60604 (Residues: 1-165; Coverage: 100%)
Gene names: UBC7, UBE2G2
Sequence domains: Ubiquitin-conjugating enzyme
Structure domains: Ubiquitin Conjugating Enzyme

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

4 review citations

E2s: structurally economical and functionally replete.
Wenzel et al. (2011)
3 more

8 mentions without citation

Solution structure and dynamics of human ubiquitin conjugating enzyme Ube2g2.
Ju et al. (2010)
7 more