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Solution NMR

Solution Structure of the major allergen of Artemisia vulgaris (Art v 1)

Released:
DOI: 10.2210/pdb2kpy/pdb
PDB entry 2kpy coloured by chain, ensemble of 20 models, front view.
PDB entry 2kpy coloured by chain, ensemble of 20 models, side view.
PDB entry 2kpy coloured by chain, ensemble of 20 models, top view.
Source organism: Artemisia vulgaris
Primary publication:
Mapping the interactions between a major pollen allergen and human IgE antibodies.
Razzera G, Gadermaier G, de Paula V, Almeida MS, Egger M, Jahn-Schmid B, Almeida FC, Ferreira F, Valente AP
Structure 18 1011-21 (2010)
PMID: 20696401

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183083 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Major pollen allergen Art v 1 Chain: A
Molecule details ›
Chain: A
Length: 108 amino acids
Theoretical weight: 10.82 KDa
Source organism: Artemisia vulgaris
Expression system: Escherichia coli
UniProt:
  • Canonical: Q84ZX5 (Residues: 25-132; Coverage: 100%)
Sequence domains: Gamma-thionin family
Structure domains: Knottin, scorpion toxin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 81%
Refinement method: torsion angle dynamics, TORSION ANGLE DYNAMICS
Expression system: Escherichia coli

Quick links

Citations

10 review citations

Allergens of weed pollen: an overview on recombinant and natural molecules.
Gadermaier et al. (2014)
9 more

3 mentions without citation

Structure of allergens and structure based epitope predictions.
Dall'antonia et al. (2014)
2 more