› 2l0e

Solution NMR

Structural and functional analysis of tm vi of the nhe1 isoform of the na+/h+ exchanger

Released:
DOI: 10.2210/pdb2l0e/pdb
PDB entry 2l0e coloured by chain, ensemble of 40 models, front view.
PDB entry 2l0e coloured by chain, ensemble of 40 models, side view.
PDB entry 2l0e coloured by chain, ensemble of 40 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural and functional analysis of transmembrane segment VI of the NHE1 isoform of the Na+/H+ exchanger.
Tzeng J, Lee BL, Sykes BD, Fliegel L
J Biol Chem 285 36656-65 (2010)
PMID: 20843797

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148672 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sodium/hydrogen exchanger 1 Chain: A
Molecule details ›
Chain: A
Length: 33 amino acids
Theoretical weight: 3.47 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P19634 (Residues: 226-250; Coverage: 3%)
Gene names: APNH1, NHE1, SLC9A1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 49%
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

2 review citations

Structural and functional insights into the cardiac Na⁺/H⁺ exchanger.
Lee et al. (2013)
1 more

2 mentions without citation

Structural and functional analysis of transmembrane segment VI of the NHE1 isoform of the Na+/H+ exchanger.
Tzeng et al. (2010)
1 more