› 2l5b

Solution NMR

Solution structure of the transmembrane domain of Bcl-2 member Harakiri in micelles

Released:
DOI: 10.2210/pdb2l5b/pdb
PDB entry 2l5b coloured by chain, ensemble of 20 models, front view.
PDB entry 2l5b coloured by chain, ensemble of 20 models, side view.
PDB entry 2l5b coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Intrinsic order and disorder in the bcl-2 member harakiri: insights into its proapoptotic activity.
Barrera-Vilarmau S, Obregón P, de Alba E
PLoS One 6 e21413 (2011)
PMID: 21731739

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126148 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Activator of apoptosis harakiri Chain: A
Molecule details ›
Chain: A
Length: 32 amino acids
Theoretical weight: 3.32 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O00198 (Residues: 61-91; Coverage: 34%)
Gene names: BID3, HRK
Sequence domains: Activator of apoptosis harakiri

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DGSA-distance geometry simulated annealing
Expression system: Not provided

Quick links

Citations

2 review citations

Functions of the C-terminal domains of apoptosis-related proteins of the Bcl-2 family.
Gómez-Fernández JC. (2014)
1 more

1 mention without citation

Intrinsic order and disorder in the bcl-2 member harakiri: insights into its proapoptotic activity.
Barrera-Vilarmau et al. (2011)