› 2l7f

Solution NMR

Solution Structure of the Pitx2 Homeodomain

Released:
DOI: 10.2210/pdb2l7f/pdb
PDB entry 2l7f coloured by chain, ensemble of 20 models, front view.
PDB entry 2l7f coloured by chain, ensemble of 20 models, side view.
PDB entry 2l7f coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Doerdelmann T, Rance M, Baird-Titus JM, Kojetin DJ

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189247 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pituitary homeobox 2 Chain: P
Molecule details ›
Chain: P
Length: 68 amino acids
Theoretical weight: 8.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q99697 (Residues: 85-144; Coverage: 19%)
Gene names: ARP1, PITX2, RGS, RIEG, RIEG1
Sequence domains: Homeodomain
Structure domains: Homeodomain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 86%
Refinement method: torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)

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