› 2l9i

Solution NMR

NMR structure of thymosin alpha-1

Released:
DOI: 10.2210/pdb2l9i/pdb
PDB entry 2l9i coloured by chain, ensemble of 21 models, front view.
PDB entry 2l9i coloured by chain, ensemble of 21 models, side view.
PDB entry 2l9i coloured by chain, ensemble of 21 models, top view.
Source organism: Homo sapiens
Primary publication:
NMR structure of human thymosin alpha-1.
Elizondo-Riojas MA, Chamow SM, Tuthill CW, Gorenstein DG, Volk DE
Biochem Biophys Res Commun 416 356-61 (2011)
PMID: 22115779

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139049 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thymosin alpha-1 Chain: A
Molecule details ›
Chain: A
Length: 29 amino acids
Theoretical weight: 3.1 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P06454 (Residues: 2-29; Coverage: 25%)
Gene names: PTMA, TMSA

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 48%
Refinement method: molecular dynamics, restrained molecular dynamics, restrained molecular dynamics and selection, average structure
Expression system: Not provided

Quick links

Citations

2 review citations

Thymosin alpha 1: A comprehensive review of the literature.
Dominari et al. (2020)
1 more

5 mentions without citation

Host Defense Peptides as Templates for Antifungal Drug Development.
Basso et al. (2020)
4 more