› 2lc6

Solution NMR

Solution structure of Par-6 Q144C/L164C

Released:
DOI: 10.2210/pdb2lc6/pdb
PDB entry 2lc6 coloured by chain, ensemble of 20 models, front view.
PDB entry 2lc6 coloured by chain, ensemble of 20 models, side view.
PDB entry 2lc6 coloured by chain, ensemble of 20 models, top view.
Source organism: Drosophila melanogaster
Primary publication:
A conformational switch in the CRIB-PDZ module of Par-6.
Whitney DS, Peterson FC, Volkman BF
Structure 19 1711-22 (2011)
PMID: 22078569

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132169 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Par-6, isoform A Chain: A
Molecule details ›
Chain: A
Length: 128 amino acids
Theoretical weight: 13.72 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O97111 (Residues: 130-255; Coverage: 36%)
Gene names: CG5884, DPar-6, DPar6, Dm-Par-6, Dm-Par6, DmPAR-6, DmPar-6, DmPar6, Dmel\CG5884, Dmel_CG5884, Dmpar6, PAR-6, PAR6, Par, Par-6, Par6, dPAR-6, dPar-6, dmPar-6, par, par-6, par6
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Chemical shift assignment: 92%
Refinement method: torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

8 review citations

Structures and target recognition modes of PDZ domains: recurring themes and emerging pictures.
Ye et al. (2013)
7 more

3 mentions without citation

A conformational switch in the CRIB-PDZ module of Par-6.
Whitney et al. (2011)
2 more