› 2lcw

Solution NMR

solution structure of FUS/TLS RRM domain

Released:
DOI: 10.2210/pdb2lcw/pdb
PDB entry 2lcw coloured by chain, ensemble of 20 models, front view.
PDB entry 2lcw coloured by chain, ensemble of 20 models, side view.
PDB entry 2lcw coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Liu X, Ren J, Niu C, Gong W, Feng W

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152977 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RNA-binding protein FUS Chain: A
Molecule details ›
Chain: A
Length: 116 amino acids
Theoretical weight: 12.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P35637 (Residues: 278-385; Coverage: 21%)
Gene names: FUS, TLS
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 91%
Refinement method: simulated annealing
Expression system: Escherichia coli

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