Function and Biology Details
Reaction catalysed:
NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150914 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Poly [ADP-ribose] polymerase 1, processed C-terminus
Molecule details ›
Chain: A
Length: 106 amino acids
Theoretical weight: 11.67 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
Sequence domains: BRCA1 C Terminus (BRCT) domain
Structure domains: BRCT domain
Length: 106 amino acids
Theoretical weight: 11.67 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
- Canonical:
P27008 (Residues: 389-487; Coverage: 10%)
Sequence domains: BRCA1 C Terminus (BRCT) domain
Structure domains: BRCT domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Chemical shift assignment:
82%
Refinement method:
simulated annealing, simulated annealing
Expression system: Escherichia coli
