› 2lg4

Solution NMR

3D solution structure of antimicrobial peptide aurelin

Released:
DOI: 10.2210/pdb2lg4/pdb
PDB entry 2lg4 coloured by chain, ensemble of 20 models, front view.
PDB entry 2lg4 coloured by chain, ensemble of 20 models, side view.
PDB entry 2lg4 coloured by chain, ensemble of 20 models, top view.
Source organism: Aurelia aurita
Primary publication:
Recombinant expression and solution structure of antimicrobial peptide aurelin from jellyfish Aurelia aurita.
Shenkarev ZO, Panteleev PV, Balandin SV, Gizatullina AK, Altukhov DA, Finkina EI, Kokryakov VN, Arseniev AS, Ovchinnikova TV
Biochem Biophys Res Commun 429 63-9 (2012)
PMID: 23137541

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170990 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Antimicrobial peptide aurelin Chain: A
Molecule details ›
Chain: A
Length: 40 amino acids
Theoretical weight: 4.31 KDa
Source organism: Aurelia aurita
Expression system: Escherichia coli
UniProt:
  • Canonical: Q0MWV8 (Residues: 45-84; Coverage: 65%)
Sequence domains: ShK domain-like
Structure domains: ShTK domain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 79%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

11 review citations

Antimicrobial peptides (AMPs): Ancient compounds that represent novel weapons in the fight against bacteria.
Ageitos et al. (2017)
10 more

10 mentions without citation

Cell Biology of Intracellular Adaptation of Mycobacterium leprae in the Peripheral Nervous System.
Hess et al. (2019)
9 more