› 2ltp

Solution NMR

Solution structure of the SANT2 domain of the human nuclear receptor corepressor 2 (NCoR2), Northeast Structural Genomics Consortium (NESG) target ID HR4636E

Released:
DOI: 10.2210/pdb2ltp/pdb
PDB entry 2ltp coloured by chain, ensemble of 20 models, front view.
PDB entry 2ltp coloured by chain, ensemble of 20 models, side view.
PDB entry 2ltp coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Montecchio M, Lemak A, Yee A, Xu C, Garcia M, Houliston S, Bellanda M, Min J, Montelione GT, Arrowsmith C, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195332 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nuclear receptor corepressor 2 Chain: A
Molecule details ›
Chain: A
Length: 89 amino acids
Theoretical weight: 10.78 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y618 (Residues: 615-685; Coverage: 3%)
Gene names: CTG26, NCOR2
Sequence domains: Myb-like DNA-binding domain
Structure domains: Homeodomain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 87%
Refinement method: restrained molecular dynamics
Expression system: Escherichia coli

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