› 2lvt

Solution NMR

Solution structure of Miz-1 zinc finger 9

Released:
DOI: 10.2210/pdb2lvt/pdb
PDB entry 2lvt coloured by chain, ensemble of 20 models, front view.
PDB entry 2lvt coloured by chain, ensemble of 20 models, side view.
PDB entry 2lvt coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
NMR structure note: solution structure of human Miz-1 zinc fingers 8 to 10.
Bédard M, Maltais L, Beaulieu ME, Bilodeau J, Bernard D, Lavigne P
J Biomol NMR 54 317-23 (2012)
PMID: 22986688

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171530 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Zinc finger and BTB domain-containing protein 17 Chain: A
Molecule details ›
Chain: A
Length: 83 amino acids
Theoretical weight: 9.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q13105 (Residues: 500-581; Coverage: 10%)
Gene names: MIZ1, ZBTB17, ZNF151, ZNF60
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 80%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 citation in other articles

Miz-1 activates gene expression via a novel consensus DNA binding motif.
Barrilleaux et al. (2014)
3 more

2 mentions without citation

A missense mutation in zbtb17 blocks the earliest steps of T cell differentiation in zebrafish.
Lawir et al. (2017)
1 more