› 2lw8

Solution NMR

NMR solution structure of Eph receptor

Released:
DOI: 10.2210/pdb2lw8/pdb
PDB entry 2lw8 coloured by chain, ensemble of 10 models, front view.
PDB entry 2lw8 coloured by chain, ensemble of 10 models, side view.
PDB entry 2lw8 coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Entry authors: Qin H, Song J

Function and Biology Details

Reaction catalysed: 
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157094 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ephrin type-A receptor 4 Chain: A
Molecule details ›
Chain: A
Length: 183 amino acids
Theoretical weight: 20.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P54764 (Residues: 29-209; Coverage: 19%)
Gene names: EPHA4, HEK8, SEK, TYRO1
Sequence domains: Ephrin receptor ligand binding domain
Structure domains: Galactose-binding domain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 63%
Refinement method: distance geometry
Expression system: Escherichia coli

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