Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domain:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Epidermal growth factor receptor (preferred)
PDBe Complex ID:
PDB-CPX-132701 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Epidermal growth factor receptor
Molecule details ›
Chains: A, B
Length: 60 amino acids
Theoretical weight: 6.78 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Epidermal growth factor receptor transmembrane-juxtamembrane segment
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Length: 60 amino acids
Theoretical weight: 6.78 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P00533 (Residues: 642-697; Coverage: 5%)
Sequence domains: Epidermal growth factor receptor transmembrane-juxtamembrane segment
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Chemical shift assignment:
39%
Refinement method:
simulated annealing
Expression system: Escherichia coli
