› 2m9n

Solution NMR

Solution Structure of (HhH)2 domain of human FAAP24

Released:
DOI: 10.2210/pdb2m9n/pdb
PDB entry 2m9n coloured by chain, ensemble of 10 models, front view.
PDB entry 2m9n coloured by chain, ensemble of 10 models, side view.
PDB entry 2m9n coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
Structure analysis of FAAP24 reveals single-stranded DNA-binding activity and domain functions in DNA damage response.
Wang Y, Han X, Wu F, Leung JW, Lowery MG, Do H, Chen J, Shi C, Tian C, Li L, Gong W
Cell Res 23 1215-28 (2013)
PMID: 23999858

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189724 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fanconi anemia core complex-associated protein 24 Chain: A
Molecule details ›
Chain: A
Length: 63 amino acids
Theoretical weight: 6.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9BTP7 (Residues: 155-215; Coverage: 28%)
Gene names: C19orf40, FAAP24
Sequence domains: Helix-hairpin-helix motif
Structure domains: 5' to 3' exonuclease, C-terminal subdomain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 81%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Function and Interactions of ERCC1-XPF in DNA Damage Response.
Faridounnia et al. (2018)
5 other articles

1 mention without citation

Structure analysis of FAAP24 reveals single-stranded DNA-binding activity and domain functions in DNA damage response.
Wang et al. (2013)