› 2m9x

Solution NMR

Solution NMR Structure of Microtubule-associated serine/threonine-protein kinase 1 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR9151A

Released:
DOI: 10.2210/pdb2m9x/pdb
PDB entry 2m9x coloured by chain, ensemble of 20 models, front view.
PDB entry 2m9x coloured by chain, ensemble of 20 models, side view.
PDB entry 2m9x coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Xu X, Eletsky A, Shastry R, Lee D, Hamilton K, Xiao R, Acton TB, Everett JK, Montelione GT, Szyperski T, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195134 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Microtubule-associated serine/threonine-protein kinase 1 Chain: A
Molecule details ›
Chain: A
Length: 112 amino acids
Theoretical weight: 13.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y2H9 (Residues: 187-287; Coverage: 6%)
Gene names: KIAA0973, MAST1, SAST
Sequence domains: Domain of unknown function (DUF1908)
Structure domains: MAST3 pre-PK domain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 89%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

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