› 2mhy

Solution NMR

Structure determination of the salamander courtship pheromone Plethodontid Modulating Factor

Released:
DOI: 10.2210/pdb2mhy/pdb
PDB entry 2mhy coloured by chain, ensemble of 20 models, front view.
PDB entry 2mhy coloured by chain, ensemble of 20 models, side view.
PDB entry 2mhy coloured by chain, ensemble of 20 models, top view.
Source organism: Plethodon shermani
Primary publication:
Structural insights into the evolution of a sexy protein: novel topology and restricted backbone flexibility in a hypervariable pheromone from the red-legged salamander, Plethodon shermani.
Wilburn DB, Bowen KE, Doty KA, Arumugam S, Lane AN, Feldhoff PW, Feldhoff RC
PLoS One 9 e96975 (2014)
PMID: 24849290

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170926 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Plethodontid modulating factor Chain: A
Molecule details ›
Chain: A
Length: 57 amino acids
Theoretical weight: 6.27 KDa
Source organism: Plethodon shermani
Expression system: Komagataella pastoris
UniProt:
  • Canonical: Q0GB44 (Residues: 20-76; Coverage: 100%)
Structure domains: CD59

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 85%
Refinement method: molecular dynamics
Expression system: Komagataella pastoris

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Citations

3 review citations

Clusters of Multiple Mutations: Incidence and Molecular Mechanisms.
Chan et al. (2015)
2 more