› 2mvw

Solution NMR

Solution structure of the TRIM19 B-box1 (B1) of human promyelocytic leukemia (PML)

Released:
DOI: 10.2210/pdb2mvw/pdb
PDB entry 2mvw coloured by chain, ensemble of 20 models, front view.
PDB entry 2mvw coloured by chain, ensemble of 20 models, side view.
PDB entry 2mvw coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
The B-box 1 dimer of human promyelocytic leukemia protein.
Huang SY, Naik MT, Chang CF, Fang PJ, Wang YH, Shih HM, Huang TH
J Biomol NMR 60 275-81 (2014)
PMID: 25355412

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151546 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein PML Chains: A, B
Molecule details ›
Chains: A, B
Length: 51 amino acids
Theoretical weight: 5.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P29590 (Residues: 120-168; Coverage: 6%)
Gene names: MYL, PML, PP8675, RNF71, TRIM19
Sequence domains: B-box zinc finger

Ligands and Environments

1 bound ligand:
Ligand ZN 4 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 86%
Refinement method: DGSA-distance geometry simulated annealing
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Who's In and Who's Out-Compositional Control of Biomolecular Condensates.
Ditlev et al. (2018)
2 more

3 mentions without citation

Structure of KAP1 tripartite motif identifies molecular interfaces required for retroelement silencing.
Stoll et al. (2019)
2 more