› 2of7

X-ray diffraction
2.3Å resolution

Structural Genomics, the crystal structure of a tetR-family transcriptional regulator from Streptomyces coelicolor A3

Released:
DOI: 10.2210/pdb2of7/pdb
PDB entry 2of7 coloured by chain, front view.
PDB entry 2of7 coloured by chain, side view.
PDB entry 2of7 coloured by chain, top view.
Source organism: Streptomyces coelicolor
Entry authors: Tan K, Xu X, Zheng H, Savchenko A, Edwards A, Joachimiak A, Midwest Center for Structural Genomics (MCSG)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190213 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH tetR-type domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 260 amino acids
Theoretical weight: 29.41 KDa
Source organism: Streptomyces coelicolor
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9EWH2 (Residues: 2-235; Coverage: 100%)
Gene names: 2SCK31.37c, SCO4977
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 9 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2
Unit cell:
a: 75.101Å b: 73.24Å c: 48.082Å
α: 90° β: 107.27° γ: 90°
R-values:
R R work R free
0.234 0.231 0.293
Expression system: Escherichia coli BL21

Quick links