› 2om5

X-ray diffraction
3.07Å resolution

N-Terminal Fragment of Human TAX1

Released:
DOI: 10.2210/pdb2om5/pdb
PDB entry 2om5 coloured by chain, front view.
PDB entry 2om5 coloured by chain, side view.
PDB entry 2om5 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The crystal structure of the ligand-binding module of human TAG-1 suggests a new mode of homophilic interaction.
Mörtl M, Sonderegger P, Diederichs K, Welte W
Protein Sci 16 2174-83 (2007)
PMID: 17766378

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169698 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Contactin-2 Chain: A
Molecule details ›
Chain: A
Length: 381 amino acids
Theoretical weight: 42.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q02246 (Residues: 34-414; Coverage: 38%)
Gene names: AXT, CNTN2, TAG1, TAX1
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: C2221
Unit cell:
a: 46.804Å b: 106.916Å c: 161.366Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.238 0.235 0.279
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Animal models of multiple sclerosis--potentials and limitations.
Mix et al. (2010)
6 more

10 mentions without citation

Homophilic interaction of the L1 family of cell adhesion molecules.
Wei et al. (2012)
9 more