› 2p57

X-ray diffraction
1.8Å resolution

GAP domain of ZNF289, an ID1-regulated zinc finger protein

Released:
DOI: 10.2210/pdb2p57/pdb
PDB entry 2p57 coloured by chain, front view.
PDB entry 2p57 coloured by chain, side view.
PDB entry 2p57 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Tong Y, Dimov S, Shen L, Zhu H, Tempel W, Landry R, Arrowsmith CH, Edwards AM, Sundstrom M, Weigelt J, Bochkarev A, Park H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185417 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ADP-ribosylation factor GTPase-activating protein 2 Chain: A
Molecule details ›
Chain: A
Length: 144 amino acids
Theoretical weight: 16.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8N6H7 (Residues: 3-130; Coverage: 25%)
Gene names: ARFGAP2, Nbla10535, ZNF289
Sequence domains: Putative GTPase activating protein for Arf
Structure domains: Arf GTPase activating protein

Ligands and Environments

2 bound ligands:
Ligand ZN 1 x ZN
Ligand UNX 3 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E
Spacegroup: P212121
Unit cell:
a: 41.027Å b: 41.165Å c: 72.808Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.196 0.241
Expression system: Escherichia coli

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