› 2p68

X-ray diffraction
1.84Å resolution

Crystal Structure of aq_1716 from Aquifex Aeolicus VF5

Released:
DOI: 10.2210/pdb2p68/pdb
PDB entry 2p68 coloured by chain, front view.
PDB entry 2p68 coloured by chain, side view.
PDB entry 2p68 coloured by chain, top view.
Source organism: Aquifex aeolicus VF5
Entry authors: Chen L, Chen L-Q, Ebihara A, Shinkai A, Kuramitsu S, Yokoyama S, Zhao M, Dillard B, Rose JP, Wang B-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP(+) = 3-oxoacyl-[acyl-carrier-protein] + NADPH
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130518 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3-oxoacyl-[acyl-carrier-protein] reductase FabG Chains: A, B
Molecule details ›
Chains: A, B
Length: 248 amino acids
Theoretical weight: 26.9 KDa
Source organism: Aquifex aeolicus VF5
Expression system: Escherichia coli
UniProt:
  • Canonical: O67610 (Residues: 1-248; Coverage: 100%)
Gene names: aq_1716, fabG
Sequence domains: Enoyl-(Acyl carrier protein) reductase
Structure domains: NAD(P)-binding Rossmann-like Domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21212
Unit cell:
a: 105.698Å b: 64.214Å c: 73.448Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.185 0.183 0.223
Expression system: Escherichia coli

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