› 2p81

Solution NMR

Engrailed homeodomain helix-turn-helix motif

Released:
DOI: 10.2210/pdb2p81/pdb
PDB entry 2p81 coloured by chain, ensemble of 25 models, front view.
PDB entry 2p81 coloured by chain, ensemble of 25 models, side view.
PDB entry 2p81 coloured by chain, ensemble of 25 models, top view.
Source organism: Drosophila melanogaster
Primary publication:
The helix-turn-helix motif as an ultrafast independently folding domain: the pathway of folding of Engrailed homeodomain.
Religa TL, Johnson CM, Vu DM, Brewer SH, Dyer RB, Fersht AR
Proc Natl Acad Sci U S A 104 9272-7 (2007)
PMID: 17517666

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136264 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Segmentation polarity homeobox protein engrailed Chain: A
Molecule details ›
Chain: A
Length: 44 amino acids
Theoretical weight: 5.42 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli
UniProt:
  • Canonical: P02836 (Residues: 469-512; Coverage: 8%)
Gene names: CG9015, en
Sequence domains: Homeodomain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Escherichia coli

Quick links

Citations

10 review citations

Combining experiment and simulation in protein folding: closing the gap for small model systems.
Schaeffer et al. (2008)
9 more

2 mentions without citation

The helix-turn-helix motif as an ultrafast independently folding domain: the pathway of folding of Engrailed homeodomain.
Religa et al. (2007)
1 more