› 2pbc

X-ray diffraction
1.8Å resolution

FK506-binding protein 2

Released:
DOI: 10.2210/pdb2pbc/pdb
PDB entry 2pbc coloured by chain, front view.
PDB entry 2pbc coloured by chain, side view.
PDB entry 2pbc coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Walker JR, Neculai D, Davis T, Butler-Cole C, Sicheri F, Weigelt J, Sundstrom M, Arrowsmith CH, Edwards AM, Bochkarev A, Dhe-Paganon S, Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed: 
Peptidylproline (omega=180) = peptidylproline (omega=0)
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150872 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidyl-prolyl cis-trans isomerase FKBP2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 102 amino acids
Theoretical weight: 11.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P26885 (Residues: 43-142; Coverage: 83%)
Gene names: FKBP13, FKBP2
Sequence domains: FKBP-type peptidyl-prolyl cis-trans isomerase
Structure domains: Chitinase A; domain 3

Ligands and Environments

1 bound ligand:
Ligand PEG 4 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P21
Unit cell:
a: 42.43Å b: 39.335Å c: 108.316Å
α: 90° β: 91.28° γ: 90°
R-values:
R R work R free
0.189 0.185 0.26
Expression system: Escherichia coli BL21(DE3)

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