› 2phu

X-ray diffraction
2.2Å resolution

Pterocarpus angolensis lectin in complex with Man-8D1D3

Released:
DOI: 10.2210/pdb2phu/pdb
PDB entry 2phu coloured by chain, front view.
PDB entry 2phu coloured by chain, side view.
PDB entry 2phu coloured by chain, top view.
Source organism: Pterocarpus angolensis
Primary publication:
How a plant lectin recognizes high mannose oligosaccharides.
Garcia-Pino A, Buts L, Wyns L, Imberty A, Loris R
Plant Physiol 144 1733-41 (2007)
PMID: 17556509

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184567 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Legume lectin domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 252 amino acids
Theoretical weight: 27.56 KDa
Source organism: Pterocarpus angolensis
UniProt:
  • Canonical: Q8GSD2 (Residues: 9-260; Coverage: 97%)
Sequence domains: Legume lectin domain
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: MAN, BMA
Carbohydrate polymer
3 bound ligands:
Ligand MAN 2 x MAN
Ligand MN 2 x MN
Ligand CA 2 x CA
1 modified residue:
Ligand PCA 2 x PCA

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P212121
Unit cell:
a: 56.696Å b: 83.348Å c: 122.69Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.174 0.174 0.209

Quick links

Citations

3 review citations

The repertoire of glycan determinants in the human glycome.
Cummings RD. (2009)
2 more

1 mention without citation

Overview of the Structure⁻Function Relationships of Mannose-Specific Lectins from Plants, Algae and Fungi.
Barre et al. (2019)