2pmu

X-ray diffraction
1.78Å resolution

Crystal structure of the DNA-binding domain of PhoP

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
PDBe Complex ID:
PDB-CPX-181473 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA-binding response regulator Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 110 amino acids
Theoretical weight: 12.79 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q7D9B8 (Residues: 137-240; Coverage: 43%)
Gene name: MT0782
Sequence domains: Transcriptional regulatory protein, C terminal
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X6A
Spacegroup: C2
Unit cell:
a: 103.884Å b: 101.129Å c: 86.93Å
α: 90° β: 126.72° γ: 90°
R-values:
R R work R free
0.198 0.196 0.238
Expression system: Escherichia coli BL21(DE3)