Function and Biology Details
Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161374 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
Molecule details ›
Chains: A, C
Length: 353 amino acids
Theoretical weight: 38.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli K-12
UniProt:
Sequence domains: Protein phosphatase 2C
Structure domains: PPM-type phosphatase domain
Length: 353 amino acids
Theoretical weight: 38.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli K-12
UniProt:
- Canonical:
Q15750 (Residues: 1-370; Coverage: 70%)
Sequence domains: Protein phosphatase 2C
Structure domains: PPM-type phosphatase domain
E3 ubiquitin-protein ligase XIAP
Molecule details ›
Chains: B, D
Length: 95 amino acids
Theoretical weight: 10.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli K-12
UniProt:
Sequence domains: Inhibitor of Apoptosis domain
Structure domains: Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
Length: 95 amino acids
Theoretical weight: 10.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli K-12
UniProt:
- Canonical: P98170 (Residues: 10-100; Coverage: 18%)
Sequence domains: Inhibitor of Apoptosis domain
Structure domains: Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
