› 2pvb

X-ray diffraction
0.91Å resolution

PIKE PARVALBUMIN (PI 4.10) AT LOW TEMPERATURE (100K) AND ATOMIC RESOLUTION (0.91 A).

Released:
DOI: 10.2210/pdb2pvb/pdb
PDB entry 2pvb coloured by chain, front view.
PDB entry 2pvb coloured by chain, side view.
PDB entry 2pvb coloured by chain, top view.
Source organism: Esox lucius
Primary publication:
Crystal structure of the EF-hand parvalbumin at atomic resolution (0.91 A) and at low temperature (100 K). Evidence for conformational multistates within the hydrophobic core.
Declercq JP, Evrard C, Lamzin V, Parello J
Protein Sci 8 2194-204 (1999)
PMID: 10548066

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-135964 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Parvalbumin beta Chain: A
Molecule details ›
Chain: A
Length: 108 amino acids
Theoretical weight: 11.43 KDa
Source organism: Esox lucius
UniProt:
  • Canonical: P02619 (Residues: 1-107; Coverage: 100%)
Sequence domains: EF-hand domain pair
Structure domains: EF-hand

Ligands and Environments

3 bound ligands:
Ligand CA 2 x CA
Ligand NH4 1 x NH4
Ligand FMT 2 x FMT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P212121
Unit cell:
a: 51.03Å b: 49.81Å c: 34.57Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.11 not available 0.132

Quick links

Citations

2 review citations

EF-hand calcium-binding proteins.
Lewit-Bentley et al. (2000)
1 more

13 mentions without citation

Mapping the BKCa channel's "Ca2+ bowl": side-chains essential for Ca2+ sensing.
Bao et al. (2004)
12 more