› 2pwa

X-ray diffraction
0.83Å resolution

Crystal Structure of the complex of Proteinase K with Alanine Boronic acid at 0.83A resolution

Released:
DOI: 10.2210/pdb2pwa/pdb
PDB entry 2pwa coloured by chain, front view.
PDB entry 2pwa coloured by chain, side view.
PDB entry 2pwa coloured by chain, top view.
Source organism: Parengyodontium album
Entry authors: Jain R, Singh N, Perbandt M, Betzel C, Sharma S, Kaur P, Srinivasan A, Singh TP

Function and Biology Details

Reaction catalysed: 
Hydrolysis of keratin, and of other proteins with subtilisin-like specificity. Hydrolyzes peptide amides.
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139275 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Proteinase K Chain: A
Molecule details ›
Chain: A
Length: 279 amino acids
Theoretical weight: 28.96 KDa
Source organism: Parengyodontium album
UniProt:
  • Canonical: P06873 (Residues: 106-384; Coverage: 76%)
Gene name: PROK
Sequence domains: Subtilase family
Structure domains: Peptidase S8/S53 domain

Ligands and Environments

4 bound ligands:
Ligand CA 1 x CA
Ligand NO3 9 x NO3
Ligand SO4 1 x SO4
Ligand B2A 2 x B2A
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P43212
Unit cell:
a: 67.302Å b: 67.302Å c: 106.506Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.12 0.12 0.136

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