2q24

X-ray diffraction
1.8Å resolution

Crystal structure of TetR transcriptional regulator SCO0520 from Streptomyces coelicolor

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-193184 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH tetR-type domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 194 amino acids
Theoretical weight: 21.06 KDa
Source organism: Streptomyces coelicolor A3(2)
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9RJL5 (Residues: 1-194; Coverage: 100%)
Gene names: SCF6.16, SCO0520
Sequence domains:
Structure domains: Tetracycline Repressor, domain 2

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: P21212
Unit cell:
a: 52.295Å b: 146.152Å c: 47.305Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.191 0.225
Expression system: Escherichia coli